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Neurog1tm1(Ccre)Cschu
Targeted Allele Detail
Summary
Symbol: Neurog1tm1(Ccre)Cschu
Name: neurogenin 1; targeted mutation 1, Carol Schuurmans
MGI ID: MGI:7612306
Synonyms: Neurog1C-CreKI
Gene: Neurog1  Location: Chr13:56398291-56399976 bp, - strand  Genetic Position: Chr13, 30.06 cM
Alliance: Neurog1tm1(Ccre)Cschu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:346003
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Neurog1tm1(Ccre)Cschu expression driven by 1 gene
 
Mutation details: A targeting vector replaced the entire coding region of the Neurog1 gene with C-Cre (amino acids 60-343 in Ascl1 locus) modified with a nuclear-localization signal, GCN4 coiled-coil domain, and flexible linker. A neomycin cassette flanked by self-deletion anchor sites was present downstream of the C-Cre cassette. (J:346003)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Neurog1 (mouse)
Summary of all recombinase alleles driven by Neurog1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Neurog1 Mutation:  19 strains or lines available
References
Original:  J:346003 Moffat A, et al., Proneural genes form a combinatorial code to diversify neocortical neural progenitor cells. bioRxiv. 2024;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory