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Tg(Fzd10-cre/ERT2)2#5Luo
Transgene Detail
Summary
Symbol: Tg(Fzd10-cre/ERT2)2#5Luo
Name: transgene insertion 2#5, Liqun Luo
MGI ID: MGI:7616786
Synonyms: Fzd10-CreER
Transgene: Tg(Fzd10-cre/ERT2)2#5Luo  Location: unknown  
Alliance: Tg(Fzd10-cre/ERT2)2#5Luo page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Fzd10-cre/ERT2)2#5Luo expression driven by 1 gene
 
Mutation detailsA 9.5 kb fragment containing upstream promoter region of mouse Frizzled10 (Fzd10) gene drives expression of a Cre/ERT2 fusion gene, which was inserted in frame with the endogenous start ATG of Fzd10. Immediately downstream of CreERT2, a cassette comprised of an IRES-taulacZ followed by SV40 polyadenylation signal was inserted into the construct. One line (2#5) was maintained for all further investigation. (J:346453)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Fzd10 (mouse)
Summary of all recombinase alleles driven by Fzd10.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:346453 Cheung G, et al., Multipotent progenitors instruct ontogeny of the superior colliculus. Neuron. 2024 Jan 17;112(2):230-246.e11
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory