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Magea4em1Prp
Endonuclease-mediated Allele Detail
Summary
Symbol: Magea4em1Prp
Name: MAGE family member A4; endonuclease-mediated mutation 1, Patrick Ryan Potts
MGI ID: MGI:7624339
Gene: Magea4  Location: ChrX:71265623-71266570 bp, + strand  Genetic Position: ChrX, 37.2 cM
Alliance: Magea4em1Prp page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: CRISPR/cas9 mediated recombination using guide RNAs created an indel mutation and frameshift. This mutation is in cis with Magea10em1Prp. (J:342299)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Magea4 Mutation:  6 strains or lines available
References
Original:  J:342299 Fon Tacer K, et al., MAGE cancer-testis antigens protect the mammalian germline under environmental stress. Sci Adv. 2019 May;5(5):eaav4832
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory