Magea10<em1Prp> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7624340)

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Magea10^em1Prp
Endonuclease-mediated Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Magea10^em1Prp
Name:	MAGE family member A10; endonuclease-mediated mutation 1, Patrick Ryan Potts
MGI ID:	MGI:7624340
Gene:	Magea10 Location: ChrX:71425476-71430464 bp, - strand Genetic Position: ChrX, 37.23 cM
Alliance:	Magea10^em1Prp page

Mutation
origin

Strain of Origin:

C57BL/6

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: CRISPR/cas9 mediated recombination using guide RNAs created an indel mutation and frameshift. This mutation is in cis with Magea4^em1Prp. (J:342299)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Magea10 Mutation:	4 strains or lines available

References

Original:	J:342299 Fon Tacer K, et al., MAGE cancer-testis antigens protect the mammalian germline under environmental stress. Sci Adv. 2019 May;5(5):eaav4832
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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