Lgr5em1(EGFP,-cre/ERT2)Yil
Endonuclease-mediated Allele Detail
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| Symbol: |
Lgr5em1(EGFP,-cre/ERT2)Yil |
| Name: |
leucine rich repeat containing G protein coupled receptor 5; endonuclease-mediated mutation 1, Omer Yilmaz |
| MGI ID: |
MGI:7624526 |
| Synonyms: |
Lgr5-2A-EGFP-2A-CreERT2 |
| Gene: |
Lgr5 Location: Chr10:115286219-115423685 bp, - strand Genetic Position: Chr10, 63.51 cM
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| Alliance: |
Lgr5em1(EGFP,-cre/ERT2)Yil page
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| Allele Type: |
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Endonuclease-mediated (No functional change, Recombinase, Reporter) |
| Mutation: |
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Insertion
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Lgr5em1(EGFP,-cre/ERT2)Yil expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Lgr5-2A-EGFP-2A-CreERT2 mice was generated by inserting P2A-EGFP-T2A-CreERT2 cassette in the endogenous Lgr5 gene locus immediately at the 5 end of the endogenous stop codon using CRISPR-Cas9 technology and zygote microinjection.
(J:347568)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Lgr5
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Lgr5 Mutation: |
58 strains or lines available
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| Original: |
J:347568 Goto N, et al., Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury. Cell Stem Cell. 2022 Aug 4;29(8):1246-1261.e6 |
| All: |
1 reference(s) |
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Analysis Tools
