About   Help   FAQ
Grem1em1(tdTomato,-cre/ERT2)Yil
Endonuclease-mediated Allele Detail
Summary
Symbol: Grem1em1(tdTomato,-cre/ERT2)Yil
Name: gremlin 1, DAN family BMP antagonist; endonuclease-mediated mutation 1, Omer Yilmaz
MGI ID: MGI:7624527
Synonyms: Grem1-2A-tdTomato-2A-CreERT2
Gene: Grem1  Location: Chr2:113579020-113588993 bp, - strand  Genetic Position: Chr2, 57.43 cM
Alliance: Grem1em1(tdTomato,-cre/ERT2)Yil page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (No functional change, Recombinase, Reporter)
Mutation:    Insertion
 
Grem1em1(tdTomato,-cre/ERT2)Yil expression driven by 1 gene
 
Mutation details: Grem1-2A-tdTomato-2A-CreERT2 mouse was generated by inserting P2A-tdTomato-T2A-CreERT2 cassette in the endogenous Grem1 gene locus immediately at the 5 end of the endogenous stop codon using CRISPR-Cas9 technology and zygote microinjection. (J:347568)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Grem1 (mouse)
Summary of all recombinase alleles driven by Grem1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grem1 Mutation:  19 strains or lines available
References
Original:  J:347568 Goto N, et al., Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury. Cell Stem Cell. 2022 Aug 4;29(8):1246-1261.e6
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory