Igs2em18(CAG-folA/cre)Smoc
Endonuclease-mediated Allele Detail
|
|
| Symbol: |
Igs2em18(CAG-folA/cre)Smoc |
| Name: |
intergenic site 2; endonuclease-mediated mutation 18, Shanghai Model Organisms Center |
| MGI ID: |
MGI:7626524 |
| Synonyms: |
Igs2em1(CAG-ddCre-V5-polyA)Smoc |
| Gene: |
Igs2 Location: unknown Genetic Position: Chr11, Syntenic
|
| Alliance: |
Igs2em18(CAG-folA/cre)Smoc page
|
|
|
|
| Allele Type: |
|
Endonuclease-mediated (Inducible, Recombinase) |
| Inducer: |
|
trimethoprim |
| Mutation: |
|
Insertion
|
| |
|
Igs2em18(CAG-folA/cre)Smoc expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
|
|
| |
|
Mutation details: CRISPR/cas9 endonuclease mediated genome editing is used to introduce P2A-trimethoprim(TMP)-inducible cre (ddCre) cassette immediately before the stop codon of Doc2b gene. Cre recombinase is fused to the destabilizing DHFR (or folA) domain, which can be transiently stabilized by the administration of TMP.
(J:238766)
|
| Inheritance: |
|
Not Specified |
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
CAG
(chicken)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Igs2 Mutation: |
72 strains or lines available
|
|
| Original: |
J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017; |
| All: |
1 reference(s) |
|
Analysis Tools
