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Gene Expression Data
Assay Details
Assay
Reference: J:74625 Shahbazian MD, et al., Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation. Hum Mol Genet. 2002 Jan 15;11(2):115-24
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7628661
Gene symbol: Mecp2
Gene name: methyl CpG binding protein 2
Antibody: anti-Mecp2
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 5I: postnatal week 19 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum cerebellar Golgi cell Present 5I Expression was highest in Golgi cells, lower in Purkinje and stellate cells, and very low in granule cells.
TS28: cerebellum cerebellar granule cell Present 5I Expression was highest in Golgi cells, lower in Purkinje and stellate cells, and very low in granule cells.
TS28: cerebellum cerebellar stellate cell Present 5I Expression was highest in Golgi cells, lower in Purkinje and stellate cells, and very low in granule cells.
TS28: cerebellum Purkinje cell Present 5I Expression was highest in Golgi cells, lower in Purkinje and stellate cells, and very low in granule cells.
Specimen 7A: postnatal week 19 (more )
Note: Double labeled: green - Mecp2; red - Gfap (assay MGI:7638777).
Structure Level Pattern Image Note
TS28: pons Present 7A , 7B
Specimen 7C: postnatal week 19 (more )
Note: Double labeled: green - Mecp2; red - Gfap (assay MGI:7638777).
Structure Level Pattern Image Note
TS28: corpus callosum Present 7C
TS28: hippocampus Present 7C
TS28: paraventricular thalamic nucleus Present 7C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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