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Gene Expression Data
Assay Details
Assay
Reference: J:347711 Morikawa M, et al., Mesenchymal cells regulate enteric neural crest cell migration via RET-GFRA1b trans-signaling. Biochem Biophys Res Commun. 2024 May 28;710:149861
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7638765
Gene symbol: Gfra1
Gene name: glial cell line derived neurotrophic factor family receptor alpha 1
Antibody: anti-GFR alpha-1 (AF560)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1E E12.0: embryonic day 12.0 (more )
Note: Double labeled: green - Gfra1; red - Acta2 (assay MGI:7638764).
Structure Level Pattern Image Note
TS20: gut Present 1E E12.0
Specimen 1E E12.5: embryonic day 12.5 (more )
Note: Double labeled: green - Gfra1; red - Acta2 (assay MGI:7638764).
Structure Level Pattern Image Note
TS20: gut Present Regionally restricted 1E E12.5 At E12.5, expression in a ring shape from anti-mesenteric side to mesenteric side.
Specimen 1E E13.0: embryonic day 13.0 (more )
Note: Double labeled: green - Gfra1; red - Acta2 (assay MGI:7638764).
Structure Level Pattern Image Note
TS21: gut Present 1E E13.0
Specimen 1E E13.5: embryonic day 13.5 (more )
Note: Double labeled: green - Gfra1; red - Acta2 (assay MGI:7638764).
Structure Level Pattern Image Note
TS21: gut Present 1E E13.5
Specimen S1 E11.5 row1: embryonic day 11.5 (more )
Note: Double labeled: green - Gfra1; red - Uchl1 (assay MGI:7638767).
Structure Level Pattern Image Note
TS19: gut Present Widespread S1_E11.5 row1 At E11.5, expression widely distributed, with trend towards stronger expression on anti-mesenteric side .
Specimen S1 E12.5 MG row1: embryonic day 12.5 (more )
Note: Double labeled: green - Gfra1; red - Uchl1 (assay MGI:7638767).
Structure Level Pattern Image Note
TS20: midgut Present Regionally restricted S1_E12.5 MG row1 At E12.5, expression in a ring shape from anti-mesenteric side to mesenteric side.
Specimen S1 E12.5 HG row1: embryonic day 12.5 (more )
Note: Double labeled: green - Gfra1; red - Uchl1 (assay MGI:7638767).
Structure Level Pattern Image Note
TS20: hindgut Present Regionally restricted S1_E12.5 HG row1 At E12.5, expression in a ring shape from anti-mesenteric side to mesenteric side.
Specimen S1 E15.5 MG row1: embryonic day 15.5 (more )
Note: Double labeled: green - Gfra1; red - Uchl1 (assay MGI:7638767).
Structure Level Pattern Image Note
TS23: hindgut Present S1_E15.5 MG row1
Specimen S1 E15.5 HG row1: embryonic day 15.5 (more )
Note: Double labeled: green - Gfra1; red - Uchl1 (assay MGI:7638767).
Structure Level Pattern Image Note
TS23: hindgut Present S1_E15.5 HG row1
Specimen S2A E11.5: embryonic day 11.5 (more )
Note: Triple labeled: red - Gfra1; green - Acta2 (assay MGI:7638764); blue - Tubb3 (assay MGI:7638763).
Structure Level Pattern Image Note
TS19: midgut Present Widespread S2A E11.5 (upper) , S2A E11.5 (lower) At E11.5, expression widely distributed, with trend towards stronger expression on anti-mesenteric side .
Specimen S2A E12.0, s2B: embryonic day 12.0 (more )
Note: Triple labeled: red - Gfra1; green - Acta2 (assay MGI:7638764); blue - Tubb3 (assay MGI:7638763).
Structure Level Pattern Image Note
TS20: midgut Present Regionally restricted S2A E12.0 (lower) , S2A E12.0 (upper) , S2B Merge , S2B GFRA1/TuJ1 Strong co-localization of expression with Acta2 in luminal region of Gfra1-expressing ring of cells.
Specimen S2A E12.5: embryonic day 12.5 (more )
Note: Triple labeled: red - Gfra1; green - Acta2 (assay MGI:7638764); blue - Tubb3 (assay MGI:7638763).
Structure Level Pattern Image Note
TS20: midgut Present Regionally restricted S2A E12.5 (lower) , S2A E12.5 (upper) At E12.5, expression in a ring shape from anti-mesenteric side to mesenteric side
Specimen S2A E13.0: embryonic day 13.0 (more )
Note: Triple labeled: red - Gfra1; green - Acta2 (assay MGI:7638764); blue - Tubb3 (assay MGI:7638763).
Structure Level Pattern Image Note
TS21: midgut Present S2A E13.0 (upper) , S2A E13.0 (lower)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory