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Sstr2tm1(cre/ERT2)Ddg
Targeted Allele Detail
Summary
Symbol: Sstr2tm1(cre/ERT2)Ddg
Name: somatostatin receptor 2; targeted mutation 1, David D Ginty
MGI ID: MGI:7643392
Synonyms: Sstr2CreER-T2a
Gene: Sstr2  Location: Chr11:113510168-113516854 bp, + strand  Genetic Position: Chr11, 79.05 cM
Alliance: Sstr2tm1(cre/ERT2)Ddg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:348651
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (C57BL/6 x 129)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Sstr2tm1(cre/ERT2)Ddg expression driven by 1 gene
 
Mutation details: The cre/ERT2 cassette followed by T2a STOP and frt flanked neo cassette was inserted directly downstream of the coding exon containing the methionine start codon for Sstr2 gene. (J:348651)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sstr2 (mouse)
Summary of all recombinase alleles driven by Sstr2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sstr2 Mutation:  33 strains or lines available
References
Original:  J:348651 Qi L, et al., A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes. Cell. 2024 Mar 14;187(6):1508-1526.e16
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory