About   Help   FAQ
Trpm8tm1(flpo)Ddg
Targeted Allele Detail
Summary
Symbol: Trpm8tm1(flpo)Ddg
Name: transient receptor potential cation channel, subfamily M, member 8; targeted mutation 1, David D Ginty
MGI ID: MGI:7643394
Synonyms: Trpm8T2a-FlpO
Gene: Trpm8  Location: Chr1:88234457-88318909 bp, + strand  Genetic Position: Chr1, 44.57 cM
Alliance: Trpm8tm1(flpo)Ddg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:348651
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (C57BL/6 x 129)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Trpm8tm1(flpo)Ddg expression driven by 1 gene
 
Mutation details: The T2a-flpo cassette followed by STOP and frt flanked neo cassette was inserted directly upstream of the stop codon in the last exon of the Trpm8 gene. (J:348651)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Trpm8 (mouse)
Summary of all recombinase alleles driven by Trpm8.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trpm8 Mutation:  61 strains or lines available
References
Original:  J:348651 Qi L, et al., A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes. Cell. 2024 Mar 14;187(6):1508-1526.e16
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory