About   Help   FAQ
Fbxo2tm1(cre/ERT2)Akg
Targeted Allele Detail
Summary
Symbol: Fbxo2tm1(cre/ERT2)Akg
Name: F-box protein 2; targeted mutation 1, Andrew K Groves
MGI ID: MGI:7645434
Gene: Fbxo2  Location: Chr4:148245078-148250881 bp, + strand  Genetic Position: Chr4, 78.68 cM
Alliance: Fbxo2tm1(cre/ERT2)Akg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:339364
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Fbxo2tm1(cre/ERT2)Akg expression driven by 1 gene
 
Mutation details: The targeting vector was designed to insert a Cre/ERT2 fusion protein into the ATG start codon of the F-box protein 2 (Fbxo2) gene. Specifically, this vector includes (from 5' to 3') a cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand binding domain), a polyadenylation signal, and a loxP-flanked neomycin resistance (neo) cassette. (J:339364)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Fbxo2 (mouse)
Summary of all recombinase alleles driven by Fbxo2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fbxo2 Mutation:  21 strains or lines available
References
Original:  J:339364 McGovern MM, et al., Fbxo2(CreERT2): A new model for targeting cells in the neonatal and mature inner ear. Hear Res. 2023 Feb;428:108686
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory