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Igs2em8(Krt18-ACE2,-cre/ERT2)Cya
Endonuclease-mediated Allele Detail
Summary
Symbol: Igs2em8(Krt18-ACE2,-cre/ERT2)Cya
Name: intergenic site 2; endonuclease-mediated mutation 8, Cyagen Biosciences
MGI ID: MGI:7657273
Synonyms: Igs2em1(K18-hACE2-2A-CreERT2)
Gene: Igs2  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance: Igs2em8(Krt18-ACE2,-cre/ERT2)Cya page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Inserted expressed sequence, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Igs2em8(Krt18-ACE2,-cre/ERT2)Cya expresses 1 gene
 
Igs2em8(Krt18-ACE2,-cre/ERT2)Cya expression driven by 1 gene
 
Mutation details: The K18 promoter-Kozak-human ACE2 CDS-P2A-CreERT2-rBG pA gene expression element was inserted into the H11 safety harbor in C57BL/6JCya mice. (J:326541)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt18 (mouse)
Summary of all recombinase alleles driven by Krt18.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igs2 Mutation:  72 strains or lines available
References
Original:  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory