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Emx2em1(cre/ERT2)Mdea
Endonuclease-mediated Allele Detail
Summary
Symbol: Emx2em1(cre/ERT2)Mdea
Name: empty spiracles homeobox 2; endonuclease-mediated mutation 1, Michael R Deans
MGI ID: MGI:7657423
Synonyms: Emx2-CreERt2, Emx2P2ACreERt2
Gene: Emx2  Location: Chr19:59447122-59453789 bp, + strand  Genetic Position: Chr19, 56.28 cM
Alliance: Emx2em1(cre/ERT2)Mdea page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Emx2em1(cre/ERT2)Mdea expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 technology, the endogenous stop codon of Emx2 gene was replaced with the P2A-cre/ERT2. (J:348705)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Emx2 (mouse)
Summary of all recombinase alleles driven by Emx2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Emx2 Mutation:  24 strains or lines available
References
Original:  J:348705 Goodrich EJ, et al., Emx2 lineage tracing reveals antecedent patterns of planar polarity in the mouse inner ear. Development. 2024 May 15;151(10):dev202425
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory