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Hcrtem1(icre)Stak
Endonuclease-mediated Allele Detail
Summary
Symbol: Hcrtem1(icre)Stak
Name: hypocretin; transgene insertion 1, Takeshi Sakurai
MGI ID: MGI:7657792
Gene: Hcrt  Location: Chr11:100652519-100653757 bp, - strand  Genetic Position: Chr11, 63.6 cM
Alliance: Hcrtem1(icre)Stak page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Hcrtem1(icre)Stak expression driven by 1 gene
    CRISPR-targeting inserted an improved cre recombinase gene at the translation initation site. (J:349098)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hcrt (mouse)
Summary of all recombinase alleles driven by Hcrt.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hcrt Mutation:  19 strains or lines available
References
Original:  J:349098 Prokofeva K, et al., Structure and Function of Neuronal Circuits Linking Ventrolateral Preoptic Nucleus and Lateral Hypothalamic Area. J Neurosci. 2023 May 31;43(22):4075-4092
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory