About   Help   FAQ
Anxa1em1(icre)Awar
Endonuclease-mediated Allele Detail
Summary
Symbol: Anxa1em1(icre)Awar
Name: annexin A1; endonuclease-mediated mutation 1, Rajeshwar Awatramani
MGI ID: MGI:7661042
Synonyms: Anxa1-iCre
Gene: Anxa1  Location: Chr19:20350798-20368035 bp, - strand  Genetic Position: Chr19, 13.83 cM
Alliance: Anxa1em1(icre)Awar page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:349179
Parent Cell Line:  PRX-B6N (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Anxa1em1(icre)Awar expression driven by 1 gene
 
Mutation details: RISPR/cas9 mediated recombination inserted a construction containing a P2A peptide, icre gene, and BGH polyA sequence after the last encoded amino acid. (J:349179)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Anxa1 (mouse)
Summary of all recombinase alleles driven by Anxa1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Anxa1 Mutation:  25 strains or lines available
References
Original:  J:349179 Azcorra M, et al., Unique functional responses differentially map onto genetic subtypes of dopamine neurons. Nat Neurosci. 2023 Oct;26(10):1762-1774
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory