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Anxa1em1(icre)Awar
Endonuclease-mediated Allele Detail
Summary
Symbol: Anxa1em1(icre)Awar
Name: annexin A1; endonuclease-mediated mutation 1, Rajeshwar Awatramani
MGI ID: MGI:7661042
Synonyms: Anxa1-iCre
Gene: Anxa1  Location: Chr19:20350798-20368035 bp, - strand  Genetic Position: Chr19, 13.83 cM
Alliance: Anxa1em1(icre)Awar page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:349179
Parent Cell Line:  PRX-B6N (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Anxa1em1(icre)Awar expression driven by 1 gene
 
Mutation details: RISPR/cas9 mediated recombination inserted a construction containing a P2A peptide, icre gene, and BGH polyA sequence after the last encoded amino acid. (J:349179)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Anxa1 (mouse)
Summary of all recombinase alleles driven by Anxa1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Anxa1 Mutation:  25 strains or lines available
References
Original:  J:349179 Azcorra M, et al., Unique functional responses differentially map onto genetic subtypes of dopamine neurons. Nat Neurosci. 2023 Oct;26(10):1762-1774
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory