Gene Expression Data
Assay Details
Assay
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Reference:
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J:314568
Haara O, et al., Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling. Development. 2012 Sep;139(17):3189-99
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7663905
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Gene symbol:
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Fgf20
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Gene name:
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fibroblast growth factor 20
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
S1A:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
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Mutant Allele(s):
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EdaTa/EdaTa Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS22: molar |
Weak |
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S1A
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Fgf20 (beta-galactosidase reporter) was highly reduced in the Eda-/-;Fgf20<+/bgal> molars compared with Fgf20<+/bgal>.
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Specimen
S1B:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S1D:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
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Mutant Allele(s):
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EdaTa/EdaTa Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS23: molar |
Weak |
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S1D
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Fgf20 (beta-galactosidase reporter) was highly reduced in the Eda-/-;Fgf20<+/bgal> molars compared with Fgf20<+/bgal>.
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Specimen
S1E:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S1G:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
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Mutant Allele(s):
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EdaTa/EdaTa Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS24: molar |
Weak |
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S1G
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Fgf20 (beta-galactosidase reporter) was highly reduced in the Eda-/-;Fgf20<+/bgal> molars compared with Fgf20<+/bgal>.
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Specimen
S1H:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S7A:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS23: molar epithelium |
Present |
Regionally restricted |
S7A
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No anterior end extension of X-gal staining was observed in the Fgf20<+/bgal> molar epithelium.
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Specimen
S7B:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf20tm1.1Dor/Fgf20tm1.1Dor
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: molar epithelium |
Present |
Regionally restricted |
S7B
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X-gal staining demonstrated anterior end extension of expression in molar 1 epithelium of Fgf20<bgal/bgal>. The extension of expression did not grow down to the mesenchyme.
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Specimen
S7C:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf20tm1.1Dor/Fgf20+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: molar epithelium |
Present |
Regionally restricted |
S7C
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No anterior end extension of X-gal staining was observed in the Fgf20<+/bgal> molar epithelium.
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Specimen
S7D:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf20tm1.1Dor/Fgf20tm1.1Dor
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: molar epithelium |
Present |
Regionally restricted |
S7D
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X-gal staining demonstrated anterior end extension of expression in molar 1 epithelium of Fgf20<bgal/bgal>. The extension of expression did not grow down to the mesenchyme.
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