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Gene Expression Data
Assay Details
Assay
Reference: J:215391 Chen Y, et al., Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease. J Biomed Sci. 2014 Jul 17;21(1):63
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7666102
Gene symbol: Wt1
Gene name: WT1 transcription factor
Antibody: anti-WT-1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1D WT1: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: renal corpuscle podocyte Present 1D WT-1 Expressed in the nuclei.
Specimen 1D WT1+NEK1: postnatal adult (more )
Note: Double labeled: brown - Wt1; purple - Nek1 (assay MGI:7666079).
Structure Cell Type Level Pattern Image Note
TS28: renal corpuscle podocyte Present 1D WT1+NEK1 left , 1D WT1+NEK1 right Expressed in the same cells with cytoplasmic staining for Nek1.
Specimen 5E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cap mesenchyme Present 5E Expressed in metanephric mesenchyme.
Specimen 5F: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: mature nephron podocyte Present 5F
Specimen 5G: postnatal newborn; Nek1kat-2J/Nek1kat-2J (more )
Structure Level Pattern Image Note
TS27: cap mesenchyme Present 5G Expressed in metanephric mesenchyme.
Specimen 5H: postnatal newborn; Nek1kat-2J/Nek1kat-2J (more )
Structure Cell Type Level Pattern Image Note
TS27: s-shaped body podocyte Present 5H Juxtamedullary glomerulus was still in S-shaped form in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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