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Gene Expression Data
Assay Details
Assay
Reference: J:283037 Khalaf B, et al., Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons. J Cell Sci. 2019 Sep 26;132(18):jcs222802
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7703253
Gene symbol: Ranbp2
Gene name: RAN binding protein 2
Antibody: RanBP2 Polyclonal Antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S3A: postnatal adult (more )
Note: Double labeled: green - Ranbp2; red - Ank3 (assay MGI:7703254).
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present S3A merge , S3A Nup358 Prominent around nuclei of ganglion cells.
TS28: retina inner plexiform layer Present S3A merge , S3A Nup358 Partial overlap with Ank3 was shown.
TS28: retina outer nuclear layer Weak S3A merge , S3A Nup358 Poorly expressed around nuclei.
TS28: retina inner nuclear layer Moderate S3A merge , S3A Nup358 Moderately expressed around nuclei.
Specimen S3B: postnatal adult (more )
Note: Double labeled: green - Ranbp2; red - Nfasc (assay MGI:7703256).
Structure Level Pattern Image Note
TS28: sciatic nerve Present Regionally restricted S3B right , S3B left Coexpressed with Nfasc at nodes of Ranvier.
Specimen S3C upper: postnatal adult (more )
Note: Double labeled: green - Ranbp2; red - Cntnap1 (assay MGI:7703257).
Structure Level Pattern Image Note
TS28: sciatic nerve Present S3C merge upper , S3C Nup358 upper Coexpressed with Cntnap1 at the paranodes.
Specimen S3C lower: postnatal adult (more )
Note: Double labeled: green - Ranbp2; red - Cntnap1 (assay MGI:7703257).
Structure Level Pattern Image Note
TS28: sciatic nerve Present S3C merge lower , S3C Nup358 lower Coexpressed with Cntnap1 at the paranodes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory