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Drd1em1(flpo)Nryn
Endonuclease-mediated Allele Detail
Summary
Symbol: Drd1em1(flpo)Nryn
Name: dopamine receptor D1; endonuclease-mediated mutation 1, Nandakumar Narayanan
MGI ID: MGI:7703312
Gene: Drd1  Location: Chr13:54205202-54209677 bp, - strand  Genetic Position: Chr13, 28.4 cM
Alliance: Drd1em1(flpo)Nryn page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Drd1em1(flpo)Nryn expression driven by 1 gene
 
Mutation details: A sgRNA (GGTTGAATGCTGTCCGCTGT) was used to insert a viral 2A oligopeptide (P2A) self cleaving peptide, to mediate ribosomal skipping, fused to a flpo recombinase sequence (flpo) at 2901 bp in the dopamine receptor D1 (Drd1) gene, immediately upstream of the stop codon in exon 2. (J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Drd1 (mouse)
Summary of all recombinase alleles driven by Drd1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Drd1 Mutation:  70 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory