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Begaintm2.1(icre)Tayk
Targeted Allele Detail
Summary
Symbol: Begaintm2.1(icre)Tayk
Name: brain-enriched guanylate kinase-associated; targeted mutation 2.1, Tayo Katano
MGI ID: MGI:7709171
Synonyms: BEGAIN-iCre-Venus
Gene: Begain  Location: Chr12:108998113-109034143 bp, - strand  Genetic Position: Chr12, 59.98 cM
Alliance: Begaintm2.1(icre)Tayk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:352512
Parent Cell Line:  RENKA (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Begaintm2.1(icre)Tayk expression driven by 1 gene
 
Mutation details: A construct consisting of a P2A sequence, improved cre, T2A sequence and 3X-Venus cassette was inserted in exon 2. Begain expressing cells could not be visualized using the Venus protein. Cre activity can be detected in neurons in the forebrain including the hippocampus. (J:352512)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Begain (mouse)
Summary of all recombinase alleles driven by Begain.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Begain Mutation:  24 strains or lines available
References
Original:  J:352512 Katano T, et al., Brain-enriched guanylate kinase-associated protein, a component of the post-synaptic density protein complexes, contributes to learning and memory. Sci Rep. 2023 Dec 12;13(1):22027
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory