Tg(Agtr1a-icre)70865/2Jgro
Transgene Detail
|
|
| Symbol: |
Tg(Agtr1a-icre)70865/2Jgro |
| Name: |
transgene insertion 70865/2, Justin Grobe |
| MGI ID: |
MGI:7709177 |
| Synonyms: |
BAC-AT1A-Cre |
| Transgene: |
Tg(Agtr1a-icre)70865/2Jgro Location: unknown
|
| Alliance: |
Tg(Agtr1a-icre)70865/2Jgro page
|
|
|
|
| Transgene Type: |
|
Transgenic (Recombinase) |
| Mutation: |
|
Insertion
|
| |
|
Tg(Agtr1a-icre)70865/2Jgro expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Agtr1a (MGI:87964) |
|
|
| |
|
Mutation details: An improved cre gene, followed by a polyadenylation sequence, was inserted into BAC clone RP24-63B19 at the initiating ATG codon of the first coding exon of the Agtr1a gene so that cre expression is driven by the regulatory sequences of the BAC gene. A single line, 70865/2, was identified with faithful transmission to offspring.
(J:352970)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Agtr1a
(mouse)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:352970 Ritter ML, et al., Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice. Hypertension. 2022 Dec;79(12):2843-2853 |
| All: |
2 reference(s) |
|
Analysis Tools
