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Pnmttm1.1(cre)Sne
Targeted Allele Detail
Summary
Symbol: Pnmttm1.1(cre)Sne
Name: phenylethanolamine-N-methyltransferase; targeted mutation 1.1, Steven N Ebert
MGI ID: MGI:7709523
Gene: Pnmt  Location: Chr11:98277449-98279006 bp, + strand  Genetic Position: Chr11, 61.75 cM, cytoband D
Alliance: Pnmttm1.1(cre)Sne page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93831
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Pnmttm1.1(cre)Sne expression driven by 1 gene
 
Mutation details: Cre recombinase and an FRT flanked neomycin resistance gene were inserted into exon 1, creating an in-frame fusion gene. The FRT flanked neo from the allele Pnmttm1(cre)Sne was removed by a Flp recombinase. (J:93831, J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pnmt (mouse)
Summary of all recombinase alleles driven by Pnmt.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pnmt Mutation:  13 strains or lines available
References
Original:  J:93831 Ebert SN, et al., Targeted insertion of the Cre-recombinase gene at the phenylethanolamine n-methyltransferase locus: A new model for studying the developmental distribution of adrenergic cells. Dev Dyn. 2004 Dec;231(4):849-58
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
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