Ucmatm1.1(flpo)Hze
Targeted Allele Detail
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| Symbol: |
Ucmatm1.1(flpo)Hze |
| Name: |
upper zone of growth plate and cartilage matrix associated; targeted mutation 1.1, Hongkui Zeng |
| MGI ID: |
MGI:7712781 |
| Synonyms: |
Ucma-IRES2-FlpO-D |
| Gene: |
Ucma Location: Chr2:4980933-4990559 bp, + strand Genetic Position: Chr2, 3.11 cM
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| Alliance: |
Ucmatm1.1(flpo)Hze page
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| Allele Type: |
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Targeted (Recombinase) |
| Mutation: |
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Insertion
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Ucmatm1.1(flpo)Hze expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The targeting construct was designed to insert after the stop codon of the upper zone of growth plate and cartilage matrix associated (Ucma) gene with (from 5' to 3') a partial Ucma genomic sequence within exon 5, an internal ribosome entry site (IRES2), flpo recombinase, a bovine growth hormone polyA sequence, an AttB sequence, a PGK promoter, a prokaryotic gb2 promoter, a neomycin resistance gene, a PGK polyA sequence, and an AttP site, followed by a 3' repetitive Ucma arm, T3 promoter, lac operon promoter, E. coli catabolite activator protein to bind DNA and activate transcription (CAP BS). Chimeric mice were bred to PhiC31-expressing mice (JAX Stock No. 007743) to remove the AttB/AttP-flanked sequences including the neo.
(J:101977)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Ucma
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ucma Mutation: |
7 strains or lines available
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| Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
| All: |
1 reference(s) |
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Analysis Tools
