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Cysltr2em1(cre)Ddg
Endonuclease-mediated Allele Detail
Summary
Symbol: Cysltr2em1(cre)Ddg
Name: cysteinyl leukotriene receptor 2; endonuclease-mediated mutation 1, David D Ginty
MGI ID: MGI:7736360
Synonyms: Cysltr2T2a-Cre
Gene: Cysltr2  Location: Chr14:73263043-73286554 bp, - strand  Genetic Position: Chr14, 38.54 cM
Alliance: Cysltr2em1(cre)Ddg page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Cysltr2em1(cre)Ddg expression driven by 1 gene
 
Mutation details: Using a guide RNA (GAATTTCAAAGCTCGATTAA) designed specific for the 3' region of the murine Cysltr2 locus close to the STOP codon, T2A-cre sequence was inserted into the 3' end of the Cysltr2 gene. (J:101977, J:348651)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cysltr2 (mouse)
Summary of all recombinase alleles driven by Cysltr2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cysltr2 Mutation:  33 strains or lines available
References
Original:  J:348651 Qi L, et al., A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes. Cell. 2024 Mar 14;187(6):1508-1526.e16
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory