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Oprk1tm1(cre)Ddg
Targeted Allele Detail
Summary
Symbol: Oprk1tm1(cre)Ddg
Name: opioid receptor, kappa 1; targeted mutation 1, David D Ginty
MGI ID: MGI:7736362
Synonyms: Oprk1T2a-Cre
Gene: Oprk1  Location: Chr1:5658689-5676354 bp, + strand  Genetic Position: Chr1, 1.89 cM, cytoband A2-A3
Alliance: Oprk1tm1(cre)Ddg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:348651
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (C57BL/6 x 129)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Oprk1tm1(cre)Ddg expression driven by 1 gene
 
Mutation details: The T2a-cre cassette followed by STOP and frt flanked neo cassette was inserted directly upstream of the stop codon in the last exon of the Trpm8 gene. (J:348651)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oprk1 (mouse)
Summary of all recombinase alleles driven by Oprk1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprk1 Mutation:  30 strains or lines available
References
Original:  J:348651 Qi L, et al., A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes. Cell. 2024 Mar 14;187(6):1508-1526.e16
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory