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Lrattm1(cre/ERT2)Jhe
Targeted Allele Detail
Summary
Symbol: Lrattm1(cre/ERT2)Jhe
Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); targeted mutation 1, Jinhan He
MGI ID: MGI:7764730
Synonyms: Lrat-CreERT2
Gene: Lrat  Location: Chr3:82799889-82811281 bp, - strand  Genetic Position: Chr3, 36.81 cM
Alliance: Lrattm1(cre/ERT2)Jhe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:354237
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (No functional change, Recombinase)
Mutation:    Insertion
 
Lrattm1(cre/ERT2)Jhe expression driven by 1 gene
    A 2A-cre/ERT2 cassette was inserted upstream of the 3'UTR via homologous recombination. (J:354237)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lrat (mouse)
Summary of all recombinase alleles driven by Lrat.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lrat Mutation:  26 strains or lines available
References
Original:  J:354237 Zhang J, et al., Sirt6 Alleviated Liver Fibrosis by Deacetylating Conserved Lysine 54 on Smad2 in Hepatic Stellate Cells. Hepatology. 2021 Mar;73(3):1140-1157
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory