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Cd7em1(dre)Xhl
Endonuclease-mediated Allele Detail
Summary
Symbol: Cd7em1(dre)Xhl
Name: CD7 antigen; endonuclease-mediated mutation 1, Xiang-Hang Luo
MGI ID: MGI:7767877
Synonyms: Cd7-Dre
Gene: Cd7  Location: Chr11:120927573-120930244 bp, - strand  Genetic Position: Chr11, 84.85 cM
Alliance: Cd7em1(dre)Xhl page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Cd7em1(dre)Xhl expression driven by 1 gene
 
Mutation details: CRISPR/cas9 mediated recombination inserted a T2A-dre recombinase cassette into exon 4 just upstream of the UTR. (J:357884)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd7 (mouse)
Summary of all recombinase alleles driven by Cd7.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd7 Mutation:  15 strains or lines available
References
Original:  J:357884 Zhou HY, et al., Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain. Cell Metab. 2023 Sep 7;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory