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Ighaem2(cre)Xidw
Endonuclease-mediated Allele Detail
Summary
Symbol: Ighaem2(cre)Xidw
Name: immunoglobulin heavy constant alpha; endonuclease-mediated mutation 2, Xiaodong Wang
MGI ID: MGI:7767879
Synonyms: Igha-Cre
Gene: Igha  Location: Chr12:113219824-113223856 bp, - strand  Genetic Position: Chr12, 62.09 cM
Alliance: Ighaem2(cre)Xidw page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Ighaem2(cre)Xidw expression driven by 1 gene
    A P2A tag and cre recombinase were added to the C terminal of Igha using CRISPR/Cas9 technology. (J:357355)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Igha (mouse)
Summary of all recombinase alleles driven by Igha.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igha Mutation:  18 strains or lines available
References
Original:  J:357355 Li Y, et al., Gut bacteria induce IgA expression in pituitary hormone-secreting cells during aging. iScience. 2023 Oct 20;26(10):107747
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory