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Tg(Atoh1-flpo/ERT2)26CAlj
Transgene Detail
Summary
Symbol: Tg(Atoh1-flpo/ERT2)26CAlj
Name: transgene insertion 26C, Alexandra L Joyner
MGI ID: MGI:7790847
Synonyms: Atoh1-FlpoER
Transgene: Tg(Atoh1-flpo/ERT2)26CAlj  Location: unknown  
Alliance: Tg(Atoh1-flpo/ERT2)26CAlj page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Atoh1-flpo/ERT2)26CAlj expression driven by 1 gene
 
Mutation details: The transgene was designed with a 1.4 kb mouse atonal bHLH transcription factor 1 (Atoh1) 3' enhancer (and a Beta-globin minimal promoter) sequence upstream of an optimized flpo recombinase/human estrogen receptor fusion gene (flpo/ERT2). The line 26C was selected. (J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Atoh1 (mouse)
Summary of all recombinase alleles driven by Atoh1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:261086 Tan IL, et al., Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3392-3397
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory