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Slc34a1em1(EGFP/cre)Jsprk
Endonuclease-mediated Allele Detail
Summary
Symbol: Slc34a1em1(EGFP/cre)Jsprk
Name: solute carrier family 34 (sodium phosphate), member 1; endonuclease-mediated mutation 1, Joo-Seop Park
MGI ID: MGI:7856708
Synonyms: Slc34a1eGFPCre
Gene: Slc34a1  Location: Chr13:55547435-55562508 bp, + strand  Genetic Position: Chr13, 29.81 cM, cytoband B
Alliance: Slc34a1em1(EGFP/cre)Jsprk page
Mutation
origin
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase, Reporter)
Mutation:    Insertion
 
Slc34a1em1(EGFP/cre)Jsprk expression driven by 1 gene
 
Mutation details: Using CRISPR technology zygote carrying Slc34a1tm1(EGFP/cre/ERT2)Bhum allele was targeted with sgRNA (GGCGATCTCGAGCCATCTGC) designed to target the cre(ERT2) sequence in the SLC34a1(GCE) mutation to introduce a stop codon after the coding sequence of cre, creating a constitutively active cre-expressing allele. (J:101977, J:361196)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc34a1 (mouse)
Summary of all recombinase alleles driven by Slc34a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc34a1 Mutation:  43 strains or lines available
References
Original:  J:361196 Chung E, et al., The thin descending limb of the loop of Henle originates from proximal tubule cells during mouse kidney development. bioRxiv. 2025;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory