About   Help   FAQ
Slc6a3em1(flpo)Rcos
Endonuclease-mediated Allele Detail
Summary
Symbol: Slc6a3em1(flpo)Rcos
Name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; endonuclease-mediated mutation 1, Rui Costa
MGI ID: MGI:7858961
Gene: Slc6a3  Location: Chr13:73684866-73726791 bp, + strand  Genetic Position: Chr13, 40.1 cM
Alliance: Slc6a3em1(flpo)Rcos page
Mutation
origin
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Slc6a3em1(flpo)Rcos expression driven by 1 gene
 
Mutation details: The TAA stop codon in exon 15 of the mouse Slc6a3 gene on mouse Chromosome 13 was replaced with a T2A-FlpO-rBG (rabbit beta-globin polyadenylation signal)-pA cassette using CRISPR/cas9 methodologies. (J:361447)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc6a3 (mouse)
Summary of all recombinase alleles driven by Slc6a3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a3 Mutation:  66 strains or lines available
References
Original:  J:361447 Fushiki A, et al., A vunerable subtype of dopaminergic neurons drives early motor deficits in Parkinson's Disease. bioRxiv. 2024;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory