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Hprt1tm1(CAG-cre,-flpo,-EYFP)Ics
Targeted Allele Detail
Summary
Symbol: Hprt1tm1(CAG-cre,-flpo,-EYFP)Ics
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Mouse Clinical Institute
MGI ID: MGI:7863540
Synonyms: Hprt1tm1(CAG-cre/flpo/EYFP)Ics
Gene: Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance: Hprt1tm1(CAG-cre,-flpo,-EYFP)Ics page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  BALB/cN
Mutation
description
Allele Type:    Targeted (Conditional ready, Recombinase, Reporter)
Mutation:    Insertion
 
Hprt1tm1(CAG-cre,-flpo,-EYFP)Ics expression driven by 1 gene
 
Mutation detailsThis allele contains a CAG-cre-2A-flpo-2A-EYFP cassette with an inserted roxed selection (NeoR) cassette and is located in the Hprt1 gene on the X chromosome. Maternal contribution observed when used as a cre deleter. Both cre and flpo recombinases are active but cre-mediated excision occurs first when bred with lines containing both floxed and flipped sequences. (J:82809)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:  1281 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory