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Tg(Nr2f2-cre/ERT2)40Ics
Transgene Detail
Summary
Symbol: Tg(Nr2f2-cre/ERT2)40Ics
Name: transgene insertion 40, Mouse Clinical Institute
MGI ID: MGI:7863612
Transgene: Tg(Nr2f2-cre/ERT2)40Ics  Location: unknown  
Alliance: Tg(Nr2f2-cre/ERT2)40Ics page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Nr2f2-cre/ERT2)40Ics expression driven by 1 gene
 
Mutation detailsThe transgene was obtained by microinjection of a circular murine BAC transgene (RP23-109L9), previously modified by recombineering at the ATG of the Nrf2f2 gene of a Cre-F3-ERT2-F3 dual cassette followed by a roxed PGK-Tn5-Kana/NeoR cassette. The roxed PGK-Tn-Kana/NeoR cassette was not removed. The subline 40 was analyzed and cryopreserved. The number of transgenic copies integrated into the genome was estimated to be one per ddPCR. The corresponding integration site was not searched. The expression of cre mRNA was observed at low level in heart, ovary and uterus (respectively 5, 1 and 2% of endogenous expression). (J:82809)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nr2f2 (mouse)
Summary of all recombinase alleles driven by Nr2f2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory