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Pou6f2em1(flpo)Jbb
Endonuclease-mediated Allele Detail
Summary
Symbol: Pou6f2em1(flpo)Jbb
Name: POU domain, class 6, transcription factor 2; endonuclease-mediated mutation 1, Jay Bikoff
MGI ID: MGI:7865233
Synonyms: Pou6f2::Flpo
Gene: Pou6f2  Location: Chr13:18295683-18797700 bp, - strand  Genetic Position: Chr13, 6.05 cM
Alliance: Pou6f2em1(flpo)Jbb page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion of gene trap vector
 
Pou6f2em1(flpo)Jbb expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing technology was used to insert a P2A-Flpo cassette directly before the stop codon in exon 8. (J:361769)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pou6f2 (mouse)
Summary of all recombinase alleles driven by Pou6f2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou6f2 Mutation:  35 strains or lines available
References
Original:  J:361769 Chapman PD, et al., A brain-wide map of descending inputs onto spinal V1 interneurons. Neuron. 2025 Feb 19;113(4):524-538.e6
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory