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Rbfox3tm1(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Rbfox3tm1(EGFP/cre/ERT2)Wtsi
Name: RNA binding protein, fox-1 homolog (C. elegans) 3; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:7867284
Gene: Rbfox3  Location: Chr11:118380588-118802423 bp, - strand  Genetic Position: Chr11, 83.22 cM
Alliance: Rbfox3tm1(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0071_2_A09
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Null/knockout, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Rbfox3tm1(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation detailsThe following elements were inserted into intron 6: FRT site, En2 splice acceptor sequence, sequence coding for F2A self-cleaving peptide, EGFP reporter gene, sequence coding for T2A self-cleaving peptide, cre/ERT2 inducible recombinase gene, SV40 poly(A) signal sequence, Rox site flanked puromycin resistance gene cassette, and a loxP site. A second loxP site was inserted into intron 9. This creates a reporter-recombinase knockout allele with floxed exons 7-9. (J:82809)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Rbfox3 (mouse)
Summary of all recombinase alleles driven by Rbfox3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbfox3 Mutation:  22 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory