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Ds Gene Detail
Summary
  • Symbol
    Ds
  • Name
    disorganization
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:94929
    NCBI Gene: 109661
  • Alliance
    gene page
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 14, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 2 genetic backgrounds
    1 images
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations in this gene cause an array of birth defects, most frequently hamartomatous skin papillai and mirror-image limb duplications.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-8903
References
more
  • Summaries
    All 15
    Phenotypes 14
  • Earliest
    J:13012 HUMMEL KP, The inheritance and expression of disorganization, an unusual mutation in the mouse. J Exp Zool. 1958 Apr;137(3):389-423
  • Latest
    J:334481 Brihn LE, Positional Cloning of the Disorganization Mutation. PhD Thesis - Case Western Reserve University. 2008;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory