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fm Gene Detail
Summary
  • Symbol
    fm
  • Name
    foam cell reticulosis
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:95563
    NCBI Gene: 14259
  • Alliance
    gene page
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome Unknown
Human Diseases
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  • Diseases
    1 with fm mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations in this gene result in the replacement of lymphoid tissue of the thymus, Peyer's patches, and to a lesser extent other tissues, by lipid-containing foam cells.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-9841
References
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  • Summaries
    All 7
    Diseases 1
    Phenotypes 6
  • Earliest
    J:275 Lyon MF, et al., Foam-cell reticulosis of mice: an inherited condition resembling Gaucher's and Niemann-Pick diseases. J Med Genet. 1965 Jun;2:99-106
  • Latest
    J:5696 Adachi M, et al., Animal model of human disease: Niemann-Pick Disease type C. Am J Pathol. 1976 Oct;85(1):229-31
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory