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H3 Gene Detail
Summary
  • Symbol
    H3
  • Name
    histocompatibility 3
  • Synonyms
    H-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:95977
    NCBI Gene: 109741
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 2, Syntenic
  • Mapping Data
    22 experiments
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
This locus was identified in developing congenic strains differing in resistance to transplantable tumors. Antigen is recognized by cytotoxic T lymphocyte response, which is H2-D1-restricted. C57BL/10 carries the a allele and B10.LP carries the b allele.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-10449, MGD-MRK-10573
References
more
  • Summaries
    All 48
    Phenotypes 1
  • Earliest
    J:119 Snell GD, et al., H-3, a 5th chromosome histocompatibility locus identified in the mouse by tumor transplantation. Proc Am Assoc Cancer Res. 1955;1(1):46 (Abstr.)
  • Latest
    J:360728 Wu Q, et al., Defects in the H3t Gene Cause an Increase in Leydig Cells With Impaired Spermatogenesis in Mice. Genes Cells. 2025;30(1):e13182
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory