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Hoxc Complex/Cluster/Region Detail
Summary
  • Symbol
    Hoxc
  • Name
    homeobox C cluster
  • Synonyms
    Hox-3, Hox-6
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:96191
    NCBI Gene: 111339
  • Cluster Members
    Hoxc13, Hoxc12, Hoxc11 ... (9 members)
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 15, cytoband F1-F3
  • Mapping Data
    13 experiments
Strain
Comparison
more
  • PCR
    5
  • RFLP
    1
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Targeted deletion of the Hoxc gene cluster results in neonatal lethality.
Sequences &
Gene Models
less
Molecular
Reagents
less
  • All nucleic 3
    Genomic 2
    Primer pair 1
Other
Accession IDs
less
MGD-MRK-10838, MGD-MRK-10864, MGD-MRK-10892
References
more
  • Summaries
    All 38
    Phenotypes 9
  • Earliest
    J:8243 Awgulewitsch A, et al., Spatial restriction in expression of a mouse homoeo box locus within the central nervous system. Nature. 1986 Mar 27-Apr 2;320(6060):328-35
  • Latest
    J:297683 Fernandez-Guerrero M, et al., Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30509-30519
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory