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Ipp Gene Detail
Summary
  • Symbol
    Ipp
  • Name
    IAP promoted placental gene
  • Synonyms
    D4Jhu8, Mipp
  • Feature Type
    protein coding gene
  • IDs
    MGI:96581
    NCBI Gene: 16351
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:116364746-116395440 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    756 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96581
 protein coding gene Chr4:116364710-116400607 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028625
 protein coding gene Chr4:117399128-117436734 (+)
A/J MGP_AJ_G0028586
 protein coding gene Chr4:112910525-112942576 (+)
AKR/J MGP_AKRJ_G0028536
 protein coding gene Chr4:115339271-115372220 (+)
BALB/cJ MGP_BALBcJ_G0028607
 protein coding gene Chr4:113536727-113567502 (+)
C3H/HeJ MGP_C3HHeJ_G0028321
 protein coding gene Chr4:116910004-116941931 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029048
 protein coding gene Chr4:121947178-121986709 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026332
 protein coding gene Chr4:106949302-106981695 (+)
CAST/EiJ MGP_CASTEiJ_G0027755
 protein coding gene Chr4:114139895-114175675 (+)
CBA/J MGP_CBAJ_G0028288
 protein coding gene Chr4:125249047-125292347 (+)
DBA/2J MGP_DBA2J_G0028436
 protein coding gene Chr4:113542839-113574031 (+)
FVB/NJ MGP_FVBNJ_G0028404
 protein coding gene Chr4:112041908-112075316 (+)
LP/J MGP_LPJ_G0028538
 protein coding gene Chr4:117616234-117650572 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028431
 protein coding gene Chr4:130246449-130281608 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029085
 protein coding gene Chr4:116493050-116532208 (+)
PWK/PhJ MGP_PWKPhJ_G0027481
 protein coding gene Chr4:110319811-110353135 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027304
 protein coding gene Chr4:112765260-112802090 (+)
WSB/EiJ MGP_WSBEiJ_G0027834
 protein coding gene Chr4:116371270-116403814 (+)



Homology
more
  • Human Ortholog
    IPP, intracisternal A particle-promoted polypeptide
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IPP, intracisternal A particle-promoted polypeptide
  • Synonyms
    KLHL27
  • Links
    NCBI Gene ID: 3652
    neXtProt AC: NX_Q9Y573
    UniProt: Q9Y573

  • Chr Location
    1p34.1; chr1:45694324-45750653 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    760
  • Tissues
    46
  • cDNA Data
    14
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028696 Ensembl Gene Model | MGI Sequence Detail 30695 C57BL/6J ±  kb
    transcript ENSMUST00000106479 Ensembl | MGI Sequence Detail 2118 Not Applicable  
    polypeptide ENSMUSP00000102088 Ensembl | MGI Sequence Detail 584 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 3
      cDNA 14

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-11445, MGD-MRK-12244, MGD-MRK-6591, MGI:92709
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 16
    • Earliest
      J:11287 Mold DE, et al., Cell lineage-specific expression of the MIPP gene. Biochem Biophys Res Commun. 1991 Jun 28;177(3):1062-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory