early conceptus |
embryo ectoderm |
embryo endoderm |
embryo mesoderm |
embryo mesenchyme |
extraembryonic component |
alimentary system |
auditory system |
branchial arches |
cardiovascular system |
connective tissue |
endocrine system |
exocrine system |
hemolymphoid system |
integumental system |
limbs |
liver and biliary system |
musculoskeletal system |
nervous system |
olfactory system |
reproductive system |
respiratory system |
urinary system |
visual system |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Transcription Start Site | Location | Distance from Gene 5'-end |
| Tssr16233 | Chr2:14234201-14234215 (+) | -17 bp |
| Tssr16234 | Chr2:14252354-14252375 (+) | 18,140 bp |
| Tssr16235 | Chr2:14263431-14263475 (+) | 29,228 bp |
| Tssr16236 | Chr2:14265987-14266037 (+) | 31,787 bp |
| Tssr16237 | Chr2:14268119-14268132 (+) | 33,901 bp |
| Tssr16238 | Chr2:14268205-14268220 (+) | 33,988 bp |
| Tssr16239 | Chr2:14271308-14271320 (+) | 37,089 bp |
| Tssr16240 | Chr2:14276509-14276520 (+) | 42,290 bp |
| Tssr16241 | Chr2:14278273-14278277 (+) | 44,050 bp |
| Tssr16242 | Chr2:14278315-14278344 (+) | 44,105 bp |
| Tssr16243 | Chr2:14278394-14278399 (+) | 44,172 bp |
| Tssr16244 | Chr2:14281089-14281099 (+) | 46,869 bp |
| Tssr16245 | Chr2:14281107-14281128 (+) | 46,893 bp |
| Tssr16246 | Chr2:14283732-14283737 (+) | 49,510 bp |
| Tssr16247 | Chr2:14284387-14284396 (+) | 50,167 bp |
| Tssr16248 | Chr2:14286953-14287001 (+) | 52,752 bp |
| Tssr16249 | Chr2:14293895-14293915 (+) | 59,680 bp |
| Tssr16250 | Chr2:14293960-14293971 (+) | 59,741 bp |
| Tssr16251 | Chr2:14298314-14298325 (+) | 64,095 bp |
| Tssr16252 | Chr2:14299624-14299637 (+) | 65,406 bp |
| Tssr16253 | Chr2:14299673-14299691 (+) | 65,457 bp |
| Tssr16254 | Chr2:14310144-14310165 (+) | 75,930 bp |
| Tssr16255 | Chr2:14311847-14311850 (+) | 77,624 bp |
| Tssr16256 | Chr2:14315710-14315716 (+) | 81,488 bp |
| Tssr16257 | Chr2:14319091-14319111 (+) | 84,876 bp |
| Tssr16258 | Chr2:14319239-14319260 (+) | 85,025 bp |
| Tssr16259 | Chr2:14320159-14320172 (+) | 85,941 bp |
| Tssr16260 | Chr2:14320991-14321004 (+) | 86,773 bp |
| Tssr16261 | Chr2:14335874-14335892 (+) | 101,658 bp |
| Tssr16262 | Chr2:14335920-14335942 (+) | 101,706 bp |
| Tssr16263 | Chr2:14335946-14336007 (+) | 101,752 bp |
| Tssr16264 | Chr2:14336182-14336193 (+) | 101,963 bp |
| Tssr16265 | Chr2:14336240-14336262 (+) | 102,026 bp |
| Tssr16266 | Chr2:14336267-14336291 (+) | 102,054 bp |
| Tssr16267 | Chr2:14336307-14336329 (+) | 102,093 bp |
| QTL | Genetic Location* | Genome Location (GRCm39) | Reference | QTL Note |
| Abhr1 | Chr2, syntenic | J:122917 | The present study fine maps two previously identified airway hyper-responsiveness QTLs on mouse Chromosome 2 named Abhr1 (10 cM) and Abhr2 (30 cM). Thirty-seven polymorphic chromosome 2 markers were genotyped in 450 (C3H/HeJ x A/J)F1 x A/J backcross animals. Mrc1 at 5 cM was identified as a potential candidate gene for Abhr1. Ptgs1 at 29 cM was identified as a potential candidate gene for Abhr2. Sequence analysis of Mrc1 and Ptgs1 sequences did not detect polymorphism between A/J and C3H/HeJ. Gene expression analysis of Mrc1 and Ptgs1 lung mRNA following induction of allergic asthma in A/J and C3H/HeJ animals was performed. Ptgs1 was found to be downregulated in both inbred strains 72 hours after allergic asthma induction; however a strain-specific expression difference was not detected. | |
| Abhr2 | Chr2, 22.83 cM | J:122917 | The present study fine maps two previously identified airway hyper-responsiveness QTLs on mouse Chromosome 2 named Abhr1 (10 cM) and Abhr2 (30 cM). Thirty-seven polymorphic chromosome 2 markers were genotyped in 450 (C3H/HeJ x A/J)F1 x A/J backcross animals. Mrc1 at 5 cM was identified as a potential candidate gene for Abhr1. Ptgs1 at 29 cM was identified as a potential candidate gene for Abhr2. Sequence analysis of Mrc1 and Ptgs1 sequences did not detect polymorphism between A/J and C3H/HeJ. Gene expression analysis of Mrc1 and Ptgs1 lung mRNA following induction of allergic asthma in A/J and C3H/HeJ animals was performed. Ptgs1 was found to be downregulated in both inbred strains 72 hours after allergic asthma induction; however a strain-specific expression difference was not detected. |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
Analysis Tools
