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Rps18 Gene Detail
Summary
  • Symbol
    Rps18
  • Name
    ribosomal protein S18
  • Synonyms
    H2-Ke3, H-2Ke3
  • Feature Type
    protein coding gene
  • IDs
    MGI:98146
    NCBI Gene: 20084
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:34170972-34174639 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98146
 protein coding gene Chr17:34170972-34174975 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023548
 protein coding gene Chr17:33901405-33905961 (-)
A/J MGP_AJ_G0023509
 protein coding gene Chr17:32735029-32739100 (-)
AKR/J MGP_AKRJ_G0023475
 protein coding gene Chr17:33129998-33133979 (-)
BALB/cJ MGP_BALBcJ_G0023512
 protein coding gene Chr17:32907255-32911317 (-)
C3H/HeJ MGP_C3HHeJ_G0023274
 protein coding gene Chr17:33486398-33494637 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023954
 protein coding gene Chr17:35154480-35188966 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021428
 protein coding gene Chr17:30237276-30241356 (-)
CAST/EiJ MGP_CASTEiJ_G0022776
 protein coding gene Chr17:33561940-33568582 (-)
CBA/J MGP_CBAJ_G0023251
 protein coding gene Chr17:36587283-36592733 (-)
DBA/2J MGP_DBA2J_G0023379
 protein coding gene Chr17:32111955-32116561 (-)
FVB/NJ MGP_FVBNJ_G0023348
 protein coding gene Chr17:31978990-31983056 (-)
LP/J MGP_LPJ_G0023457
 protein coding gene Chr17:34176613-34180615 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023370
 protein coding gene Chr17:35635665-35639803 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023995
 protein coding gene Chr17:33458176-33462238 (-)
PWK/PhJ MGP_PWKPhJ_G0022524
 protein coding gene Chr17:31026732-31031204 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022340
 protein coding gene Chr17:31421245-31426642 (-)
WSB/EiJ MGP_WSBEiJ_G0022836
 protein coding gene Chr17:33497108-33501539 (-)



Homology
more
  • Human Ortholog
    RPS18, ribosomal protein S18
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPS18, ribosomal protein S18
  • Synonyms
    D6S218E, HKE3, KE-3, KE3, S18, uS13
  • Links
    NCBI Gene ID: 6222
    neXtProt AC: NX_P62269
    UniProt: P62269

  • Chr Location
    6p21.32; chr6:33272075-33276511 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a gene trap allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    10
  • cDNA Data
    15
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20084 NCBI Gene Model | MGI Sequence Detail 3668 C57BL/6J ±  kb
transcript NM_011296 RefSeq | MGI Sequence Detail 549 ZRU/MplStud  
polypeptide P62270 UniProt | EBI | MGI Sequence Detail 152 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • PDB
    7CPU, 7CPV, 7LS1, 7LS2
  • InterPro Domains
    IPR001892 Small ribosomal subunit protein uS13
    IPR018269 Small ribosomal subunit protein uS13, conserved site
    IPR027437 Small ribosomal subunit protein uS13, C-terminal
    IPR010979 Small ribosomal subunit protein uS13-like, H2TH
  • GlyGen
    P62270 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 25
    Genomic 4
    cDNA 16
    Primer pair 2
    Other 3

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-10393, MGD-MRK-14172, MGD-MRK-19439
References
more
  • Summaries
    All 47
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:32331 Michot B, et al., Sequence of the 3'-terminal domain of mouse 18 S rRNA. Conservation of structural features with other pro- and eukaryotic homologs. FEBS Lett. 1982 Jun 7;142(2):260-6
  • Latest
    J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory