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Atp1b3 Gene Detail
Summary
  • Symbol
    Atp1b3
  • Name
    ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Feature Type
    protein coding gene
  • IDs
    MGI:107788
    NCBI Gene: 11933
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96214708-96246368 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 50.31 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    871 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107788
 protein coding gene Chr9:96214708-96246495 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035143
 protein coding gene Chr9:97517694-97552290 (-)
A/J MGP_AJ_G0035124
 protein coding gene Chr9:94113716-94147314 (-)
AKR/J MGP_AKRJ_G0035056
 protein coding gene Chr9:96410718-96444451 (-)
BALB/cJ MGP_BALBcJ_G0035117
 protein coding gene Chr9:93802174-93836849 (-)
C3H/HeJ MGP_C3HHeJ_G0034827
 protein coding gene Chr9:96820101-96852118 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035637
 protein coding gene Chr9:100312791-100346176 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032538
 protein coding gene Chr9:91932443-91968979 (-)
CAST/EiJ MGP_CASTEiJ_G0034139
 protein coding gene Chr9:96580063-96614472 (-)
CBA/J MGP_CBAJ_G0034795
 protein coding gene Chr9:103797184-103830505 (-)
DBA/2J MGP_DBA2J_G0034957
 protein coding gene Chr9:93639320-93672268 (-)
FVB/NJ MGP_FVBNJ_G0034905
 protein coding gene Chr9:92490201-92523204 (-)
LP/J MGP_LPJ_G0035036
 protein coding gene Chr9:97785331-97821043 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034944
 protein coding gene Chr9:105791060-105827266 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035659
 protein coding gene Chr9:96643493-96673531 (-)
PWK/PhJ MGP_PWKPhJ_G0033846
 protein coding gene Chr9:93804726-93837582 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033681
 protein coding gene Chr9:96690425-96721951 (-)
WSB/EiJ MGP_WSBEiJ_G0034259
 protein coding gene Chr9:96505558-96539422 (-)



Homology
more
  • Human Ortholog
    ATP1B3, ATPase Na+/K+ transporting subunit beta 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP1B3, ATPase Na+/K+ transporting subunit beta 3
  • Synonyms
    ATPB-3, CD298
  • Links
    NCBI Gene ID: 483
    neXtProt AC: NX_P54709
    UniProt: P54709

  • Chr Location
    3q23; chr3:141876124-141926549 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    56
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    862
  • Tissues
    134
  • cDNA Data
    211
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 11933 NCBI Gene Model | MGI Sequence Detail 31661 C57BL/6J ±  kb
    transcript NM_001357213 RefSeq | MGI Sequence Detail 2617 ZRU/MplStud  
    polypeptide P97370 UniProt | EBI | MGI Sequence Detail 278 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000001934 sodium/potassium-transporting ATPase subunit beta-3
      (term hierarchy)
    • InterPro Domains
      IPR000402 Sodium/potassium-transporting ATPase subunit beta
      IPR038702 Sodium/potassium-transporting ATPase subunit beta superfamily
    • GlyGen
      P97370 3 sites, 9 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 216
      Genomic 1
      cDNA 212
      Primer pair 3

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-36365, MGI:2142936, MGI:2143299, MGI:2147910
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 8
      Gene Ontology 9
      Phenotypes 10
    • Earliest
      J:35336 Malik N, et al., Identification of the mammalian Na,K-ATPase 3 subunit. J Biol Chem. 1996 Sep 13;271(37):22754-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory