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Ankrd24 Gene Detail
Summary
  • Symbol
    Ankrd24
  • Name
    ankyrin repeat domain 24
  • Synonyms
    4631433D01Rik, 5730519E19Rik, D10Bur2e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890394
    NCBI Gene: 70615
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81464374-81483444 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    456 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890394
 protein coding gene Chr10:81464352-81483446 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017570
 protein coding gene Chr10:82366297-82385375 (+)
A/J MGP_AJ_G0017548
 protein coding gene Chr10:79435360-79454361 (+)
AKR/J MGP_AKRJ_G0017509
 protein coding gene Chr10:81613840-81632920 (+)
BALB/cJ MGP_BALBcJ_G0017510
 protein coding gene Chr10:79664231-79685797 (+)
C3H/HeJ MGP_C3HHeJ_G0017333
 protein coding gene Chr10:81721910-81744477 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017964
 protein coding gene Chr10:85184381-85203409 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015653
 protein coding gene Chr10:75630800-75650749 (+)
CAST/EiJ MGP_CASTEiJ_G0016900
 protein coding gene Chr10:81972581-81992112 (+)
CBA/J MGP_CBAJ_G0017305
 protein coding gene Chr10:88535450-88558857 (+)
DBA/2J MGP_DBA2J_G0017411
 protein coding gene Chr10:78639535-78662120 (+)
FVB/NJ MGP_FVBNJ_G0017405
 protein coding gene Chr10:77911890-77937795 (+)
LP/J MGP_LPJ_G0017482
 protein coding gene Chr10:82818624-82837667 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017431
 protein coding gene Chr10:90351217-90372805 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018005
 protein coding gene Chr10:81632364-81652659 (+)
PWK/PhJ MGP_PWKPhJ_G0016681
 protein coding gene Chr10:78550748-78572831 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016471
 protein coding gene Chr10:80581336-80600190 (+)
WSB/EiJ MGP_WSBEiJ_G0016960
 protein coding gene Chr10:81682022-81703502 (+)



Homology
more
  • Human Ortholog
    ANKRD24, ankyrin repeat domain 24
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD24, ankyrin repeat domain 24
  • Links
    NCBI Gene ID: 170961
    neXtProt AC: NX_Q8TF21
    UniProt: Q8TF21

  • Chr Location
    19p13.3; chr19:4182689-4224814 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    767
  • Tissues
    5
  • cDNA Data
    21
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054708 Ensembl Gene Model | MGI Sequence Detail 19071 C57BL/6J ±  kb
transcript ENSMUST00000119336 Ensembl | MGI Sequence Detail 3561 Not Applicable  
polypeptide ENSMUSP00000112932 Ensembl | MGI Sequence Detail 985 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    14 Sequences
  • Protein Ontology
    PR:000030955 ankyrin repeat domain-containing protein 24
    (term hierarchy)
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR036770 Ankyrin repeat-containing domain superfamily
    IPR050842 Cul2-RING E3 Ligase Substrate-Recognition Fem-1
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 22
    Genomic 1
    cDNA 21

    Microarray probesets 5
Other
Accession IDs
less
MGI:1917865, MGI:1926000
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 20
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory