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Slc38a10 Gene Detail
Summary
  • Symbol
    Slc38a10
  • Name
    solute carrier family 38, member 10
  • Synonyms
    1810073N04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919305
    NCBI Gene: 72055
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:119994786-120042172 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 83.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1256 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919305
 protein coding gene Chr11:119994777-120042177 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019492
 protein coding gene Chr11:124542868-124591938 (-)
A/J MGP_AJ_G0019460
 protein coding gene Chr11:119007344-119054698 (-)
AKR/J MGP_AKRJ_G0019430
 protein coding gene Chr11:122587548-122635321 (-)
BALB/cJ MGP_BALBcJ_G0019435
 protein coding gene Chr11:119363927-119411282 (-)
C3H/HeJ MGP_C3HHeJ_G0019241
 protein coding gene Chr11:122908741-122956077 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019884
 protein coding gene Chr11:128316637-128364889 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017509
 protein coding gene Chr11:116013473-116061269 (-)
CAST/EiJ MGP_CASTEiJ_G0018795
 protein coding gene Chr11:124393041-124442825 (-)
CBA/J MGP_CBAJ_G0019212
 protein coding gene Chr11:133326508-133377462 (-)
DBA/2J MGP_DBA2J_G0019324
 protein coding gene Chr11:118373351-118421816 (-)
FVB/NJ MGP_FVBNJ_G0019316
 protein coding gene Chr11:118066625-118113820 (-)
LP/J MGP_LPJ_G0019396
 protein coding gene Chr11:124850720-124899950 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019349
 protein coding gene Chr11:132189501-132241911 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019923
 protein coding gene Chr11:123269478-123320304 (-)
PWK/PhJ MGP_PWKPhJ_G0018561
 protein coding gene Chr11:119801441-119849670 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018353
 protein coding gene Chr11:123039010-123089931 (-)
WSB/EiJ MGP_WSBEiJ_G0018847
 protein coding gene Chr11:123268117-123316447 (-)



Homology
more
  • Human Ortholog
    SLC38A10, solute carrier family 38 member 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC38A10, solute carrier family 38 member 10
  • Synonyms
    PP1744, SNAT10
  • Links
    NCBI Gene ID: 124565
    neXtProt AC: NX_Q9HBR0
    UniProt: Q9HBR0

  • Chr Location
    17q25.3; chr17:81244811-81295547 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotypes from 2 alleles in 4 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice exhibit a fragile skeleton, reduced adiposity, lean body mass, body weight/length, long bone length and bone mineral density, increased creatinine levels, reduced amylase and serum albumin levels, increased energy efficiency and oxygen consumption, and altered liver physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    944
  • Tissues
    100
  • cDNA Data
    199
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000061306 Ensembl Gene Model | MGI Sequence Detail 47387 C57BL/6J ±  kb
    transcript ENSMUST00000103018 Ensembl | MGI Sequence Detail 4578 Not Applicable  
    polypeptide ENSMUSP00000099307 Ensembl | MGI Sequence Detail 1090 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 199
      cDNA 199

      Microarray probesets 10
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 19
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory