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Gmeb1 Gene Detail
Summary
  • Symbol
    Gmeb1
  • Name
    glucocorticoid modulatory element binding protein 1
  • Synonyms
    1110050A04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135604
    NCBI Gene: 56809
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:131948336-131988913 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 64.99 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1018 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135604
 protein coding gene Chr4:131948336-131988919 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028865
 protein coding gene Chr4:134355775-134397967 (-)
A/J MGP_AJ_G0028824
 protein coding gene Chr4:128774099-128816256 (-)
AKR/J MGP_AKRJ_G0028777
 protein coding gene Chr4:132391461-132434567 (-)
BALB/cJ MGP_BALBcJ_G0028847
 protein coding gene Chr4:129383279-129426970 (-)
C3H/HeJ MGP_C3HHeJ_G0028561
 protein coding gene Chr4:132635541-132686594 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029289
 protein coding gene Chr4:139193459-139243073 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026561
 protein coding gene Chr4:121858147-121896883 (-)
CAST/EiJ MGP_CASTEiJ_G0027994
 protein coding gene Chr4:130710229-130755352 (-)
CBA/J MGP_CBAJ_G0028527
 protein coding gene Chr4:142764755-142811364 (-)
DBA/2J MGP_DBA2J_G0028676
 protein coding gene Chr4:129198145-129239464 (-)
FVB/NJ MGP_FVBNJ_G0028643
 protein coding gene Chr4:128046188-128087552 (-)
LP/J MGP_LPJ_G0028777
 protein coding gene Chr4:134507062-134553994 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028669
 protein coding gene Chr4:147361216-147409978 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029327
 protein coding gene Chr4:132791783-132836177 (-)
PWK/PhJ MGP_PWKPhJ_G0027715
 protein coding gene Chr4:125873746-125917922 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027541
 protein coding gene Chr4:128664009-128706621 (-)
WSB/EiJ MGP_WSBEiJ_G0028074
 protein coding gene Chr4:132968578-133017635 (-)



Homology
more
  • Human Ortholog
    GMEB1, glucocorticoid modulatory element binding protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GMEB1, glucocorticoid modulatory element binding protein 1
  • Synonyms
    P96PIF, PIF96
  • Links
    NCBI Gene ID: 10691
    neXtProt AC: NX_Q9Y692
    UniProt: Q9Y692

  • Chr Location
    1p35.3; chr1:28668229-28719353 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    875
  • Tissues
    164
  • cDNA Data
    70
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028901 Ensembl Gene Model | MGI Sequence Detail 40578 C57BL/6J ±  kb
transcript ENSMUST00000168553 Ensembl | MGI Sequence Detail 6523 Not Applicable  
polypeptide ENSMUSP00000131331 Ensembl | MGI Sequence Detail 562 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    cDNA 70
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:1916030, MGI:2140217, MGI:2140310
References
more
  • Summaries
    All 53
    Developmental Gene Expression 9
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:69173 Jimenez-Lara AM, et al., Cloning of a mouse glucocorticoid modulatory element binding protein, a new member of the KDWK family. FEBS Lett. 2000 Feb 25;468(2-3):203-10
  • Latest
    J:277818 Tuesta LM, et al., In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function. Nat Commun. 2019 Jun 7;10(1):2508
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory