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Nxt2 Gene Detail
Summary
  • Symbol
    Nxt2
  • Name
    nuclear transport factor 2-like export factor 2
  • Synonyms
    6330587F24Rik, P15-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147914
    NCBI Gene: 237082
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:141009766-141022688 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 63.02 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    314 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147914
 protein coding gene ChrX:141009766-141022696 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036148
 protein coding gene ChrX:139724442-139736188 (+)
A/J MGP_AJ_G0036125
 protein coding gene ChrX:139127110-139139905 (+)
AKR/J MGP_AKRJ_G0036051
 protein coding gene ChrX:143578117-143590799 (+)
BALB/cJ MGP_BALBcJ_G0036116
 protein coding gene ChrX:137359355-137374130 (+)
C3H/HeJ MGP_C3HHeJ_G0035824
 protein coding gene ChrX:139834285-139847969 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036639
 protein coding gene ChrX:143746669-143761041 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033463
 protein coding gene ChrX:130697464-130707506 (+)
CAST/EiJ MGP_CASTEiJ_G0035115
 protein coding gene ChrX:120546052-120562185 (+)
CBA/J MGP_CBAJ_G0035801
 protein coding gene ChrX:148233280-148246761 (+)
DBA/2J MGP_DBA2J_G0035959
 protein coding gene ChrX:138198464-138210412 (+)
FVB/NJ MGP_FVBNJ_G0035893
 protein coding gene ChrX:137418775-137429701 (+)
LP/J MGP_LPJ_G0036050
 protein coding gene ChrX:140675324-140688304 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035929
 protein coding gene ChrX:155844250-155869219 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036676
 protein coding gene ChrX:139035246-139046884 (+)
PWK/PhJ MGP_PWKPhJ_G0034809
 protein coding gene ChrX:117360817-117374900 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034634
 protein coding gene ChrX:121066496-121077526 (+)
WSB/EiJ MGP_WSBEiJ_G0035250
 protein coding gene ChrX:137431691-137441653 (+)



Homology
more
  • Human Ortholog
    NXT2, nuclear transport factor 2 like export factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NXT2, nuclear transport factor 2 like export factor 2
  • Synonyms
    P15-2
  • Links
    NCBI Gene ID: 55916
    neXtProt AC: NX_Q9NPJ8
    UniProt: Q9NPJ8

  • Chr Location
    Xq23; chrX:109535781-109544698 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Male mice homozygous for a null allele display normal fertility and testis morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    32
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042271 Ensembl Gene Model | MGI Sequence Detail 12923 C57BL/6J ±  kb
transcript ENSMUST00000112916 Ensembl | MGI Sequence Detail 2532 Not Applicable  
polypeptide ENSMUSP00000108538 Ensembl | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:263089 Khan M, et al., The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Sci Rep. 2018 Mar 21;8(1):4975
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory