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Gene Expression Data
Assay Details
Assay
Reference: J:71879 Bernier G, et al., Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium. Development. 2001 Oct;128(20):3987-94
Assay type: RNA in situ
MGI Accession ID: MGI:2153753
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4C, +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present 4C +/+
TS15: future midbrain Present 4C +/+ Expression in the pre-tectum.

Specimen 4C, -/-: embryonic day 9.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present 4C -/- Expression in this mutant is the same as in wild-type embryos.
TS15: future midbrain Present 4C -/- Expression in the pre-tectum. Expression in this mutant is the same as in wild-type embryos.

Specimen 4C, +/+, inset: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present Regionally restricted 4C inset +/+ Expression in the retinal plate.

Specimen 4C, -/-, inset: embryonic day 9.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present Regionally restricted 4C inset -/- Expression in the retinal plate. Expression in this mutant is he same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory