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Gene Expression Data
Assay Details
Assay
Reference: J:3684 Smith DE, et al., Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development [published erratum appears in Development 1993 Mar;117(3):preceding table of contents]. Development. 1992 Dec;116(4):1033-9
Assay type: RNA in situ
MGI Accession ID: MGI:2153809
Gene symbol: Snai1
Gene name: snail family zinc finger 1
Probe: Sna probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4B: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS10: embryo mesoderm Strong 4B
TS10: parietal endoderm Strong 4B
TS10: primitive streak Strong 4B

Specimen 4C: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS10: embryo mesoderm Strong 4C
TS10: parietal endoderm Strong 4C
TS10: primitive streak Strong 4C

Specimen 5B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS12: head mesenchyme Strong 5B
TS12: trunk unsegmented mesenchyme Strong 5B
TS12: neural ectoderm Absent 5B No expression in neuroepithelium.

Specimen 5C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS12: trunk unsegmented mesenchyme Present 5C

Specimen 5E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trunk unsegmented mesenchyme Strong 5E
TS13: neural ectoderm Absent 5E

Specimen 6A,C: embryonic day 8.5 (more )
Note: 7 somite-stage.
Structure Level Pattern Image Note
TS12: head mesenchyme Present 6A , 6C Transcripts in all cephalic mesenchyme.
TS12: head mesenchyme derived from neural crest Present Regionally restricted 6C , 6A Expression in neural crest cells delaminating from the lateral edge of the hindbrain epithelium.

Specimen 7B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Very strong 7B
TS15: forelimb bud ectoderm Absent 7B No expression in the apical ectodermal ridge.
TS15: trunk paraxial mesenchyme Present 7B
TS15: trunk mesenchyme Present Regionally restricted 7B Expression in lateral mesoderm.
TS15: future spinal cord Absent 7B
TS15: gut Absent 7B No expression in gut endoderm.

Specimen 7C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo mesenchyme Present 7C Authors report expression in most mesenchymal cells, whether of neural crest or mesodermal origin.
TS15: central nervous system Absent 7C Entirely absent from neuroepithelium.

Specimen 7D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trunk sclerotome Strong 7D In somites, highest levels of expression in the sclerotome.
TS15: trunk dermomyotome Present Regionally restricted 7D Lower levels in the myotome; largely absent from the dermatome.

Specimen 7E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 7E Authors report that expression is similar to that observed at 9.5 dpc.
TS17: embryo mesenchyme Strong 7E High levels in majority of mesenchymal cells, of neural crest or of mesodermal origin.
TS17: dorsal root ganglion Absent 7E No expression in neuronal derivatives of both cranial and trunk neural crest, such as trigeminal and dorsal root ganglia.
TS17: trigeminal ganglion Absent 7E No expression in neuronal derivatives of both cranial and trunk neural crest, such as trigeminal and dorsal root ganglia.
TS17: brain Absent 7E No expression in neuroepithelium of the brain or spinal cord.
TS17: future spinal cord Absent 7E No expression in neuroepithelium of the brain or spinal cord.

Specimen 7F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lung Strong Regionally restricted 7F High levels of expression in mesenchyme surrounding the epithelial layer of a developing lung bud.

Specimen not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo Present Regionally restricted Authors report diminished overall level of expression.

Specimen 8A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nose Strong Regionally restricted 8A High levels of expression in condensing nasal cartilage.
TS21: mandible mesenchyme Strong Regionally restricted 8A High levels of expression in condensing mandibular cartilage.
TS21: lateral ventricle choroid plexus Present 8A

Specimen 8B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lateral ventricle choroid plexus Present Regionally restricted 8B Authors report expression in the mesenchymal layer of the choroid plexus.
TS21: head mesenchyme Present Regionally restricted 8B High levels of expression in mesenchyme migrating into the involuting choroid plexus neuroepithelium.

Specimen 8C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw molar mesenchyme Strong Regionally restricted 8C Intense expression in condensing mesenchyme beneath the first molar tooth bud.
TS21: upper jaw molar mesenchyme Strong Regionally restricted 8C Intense expression in condensing mesenchyme beneath the first molar tooth bud.

Specimen 8D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: metanephros Present Regionally restricted 8D Expression in metanephric mesenchyme, but not in glomerular epithelium.

Specimen 8E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung Present Regionally restricted 8E Expression in lung mesenchyme, but not in bronchial epithelium.
TS21: axial skeleton Present Regionally restricted 8E Expression in condensing cartilage of the prevertebra.
TS21: spinal ganglion Absent 8E

Specimen 8F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: head mesenchyme Strong Regionally restricted 8F High levels of expression in mesenchyme in the snout.
TS24: vibrissa dermal component Very strong Regionally restricted 8F Strongest in mesenchyme condensing around vibrissa follicles.

Specimen 8G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: foot mesenchyme Present Regionally restricted 8G Expression in cartilage of the hindfoot plate.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/03/2024
MGI 6.24
The Jackson Laboratory